Mouse kappa-opioid receptor mRNA differential transport in neurons.

  title={Mouse kappa-opioid receptor mRNA differential transport in neurons.},
  author={Jing Bi and Xinli Hu and Horace H. Loh and L N Wei},
  journal={Molecular pharmacology},
  volume={64 3},
Three kappa-opioid receptor (KOR) mRNA isoforms have been detected in different parts of the central nervous system. At the cellular level, three KOR mRNA isoforms are also differentially distributed in the axons and cell bodies of adult mouse trigeminal neurons, as well as in the processes and cell bodies of differentiated P19 neurons. To determine the molecular basis underlying differential distribution of KOR mRNA isoforms, a GFP-fused RNA binding domain, MS2, was generated and used to trace… CONTINUE READING

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