Mouse isolated perfused heart: characteristics and cautions.

  title={Mouse isolated perfused heart: characteristics and cautions.},
  author={Fiona J Sutherland and Michael J. Shattock and Kathryn E Baker and David J. Hearse},
  journal={Clinical and experimental pharmacology & physiology},
  volume={30 11},
1. Owing to the considerable potential for manipulating the murine genome and, as a consequence, the increasing availability of genetically modified models of cardiovascular diseases, the mouse is fast becoming a cornerstone of animal research. However, progress in the use of various murine preparations is hampered by the lack of facilities and skills for… CONTINUE READING