Mouse intestine selects nonmotile flhDC mutants of Escherichia coli MG1655 with increased colonizing ability and better utilization of carbon sources.

@article{Leatham2005MouseIS,
  title={Mouse intestine selects nonmotile flhDC mutants of Escherichia coli MG1655 with increased colonizing ability and better utilization of carbon sources.},
  author={M. Leatham and Sarah J. Stevenson and Eric J. Gauger and Karen Angeliki Krogfelt and Jeremy J. Lins and Traci Haddock and Steven M. Autieri and Tyrrell Conway and Paul S. Cohen},
  journal={Infection and immunity},
  year={2005},
  volume={73 12},
  pages={8039-49}
}
D-gluconate which is primarily catabolized via the Entner-Doudoroff (ED) pathway, has been implicated as being important for colonization of the streptomycin-treated mouse large intestine by Escherichia coli MG1655, a human commensal strain. In the present study, we report that an MG1655 Deltaedd mutant defective in the ED pathway grows poorly not only on gluconate as a sole carbon source but on a number of other sugars previously implicated as being important for colonization, including L… CONTINUE READING

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