Mouse hepatitis virus type 3 infection provokes a decrease in the number of sinusoidal endothelial cell fenestrae both in vivo and in vitro.

@article{Steffan1995MouseHV,
  title={Mouse hepatitis virus type 3 infection provokes a decrease in the number of sinusoidal endothelial cell fenestrae both in vivo and in vitro.},
  author={A M Steffan and Carlos Augusto Pereira and Annick Bingen and Madelyn Valle and J. Pinto – Martin and Françoise Koehren and Cathy Royer and J L Gendrault and Andr{\'e} Kirn},
  journal={Hepatology},
  year={1995},
  volume={22 2},
  pages={395-401}
}
Fenestrations of hepatic endothelial cells play an active role as a sieving barrier allowing extensive exchange between the blood and liver parenchyma. Alteration of these structures may be induced in the course of various pathological events and provoke important perturbations of liver function. We demonstrate here that sinusoidal endothelial cells are permissive for mouse hepatitis virus 3 (MHV3) in vivo and in vitro and that this infection leads to a striking decrease in the number of… CONTINUE READING

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