The genome-wide molecular regulation of mouse gastrulation embryo
- BiologyScience China Life Sciences
This review outlines the recent progresses and the future directions in studies of genome activity for the regulation of mouse embryogenesis at gastrulation and outlines the molecular mechanisms behind this fundamental developmental process.
Early endoderm development in vertebrates: lineage differentiation and morphogenetic function.
- BiologyCurrent opinion in genetics & development
Mouse gastrulation: Attributes of transcription factor regulatory network for epiblast patterning
- BiologyDevelopment, growth & differentiation
The developmental‐spatial transcriptome of the gastrulating embryo revealed the concerted and interactive activity of the gene regulatory network anchored by development‐related transcription factors, which offer novel insights into the regionalization of tissue fates and enable tracking of the progression of epiblast patterning.
Gastrula organiser and embryonic patterning in the mouse.
- BiologySeminars in cell & developmental biology
Mouse gastrulation: Coordination of tissue patterning, specification and diversification of cell fate
- BiologyMechanisms of Development
Conserved requirement of Lim1 function for cell movements during gastrulation.
- BiologyDevelopmental cell
Gastruloids: Pluripotent stem cell models of mammalian gastrulation and embryo engineering.
- BiologyDevelopmental biology
Formation of the Embryonic Head in the Mouse: Attributes of a Gene Regulatory Network.
- BiologyCurrent topics in developmental biology
SHOWING 1-10 OF 314 REFERENCES
Gastrulation in the mouse embryo: Ultrastructural and molecular aspects of germ layer morphogenesis
- BiologyMicroscopy research and technique
To this date, genes that are expressed during mouse gastrulation mostly encode cell surface adhesion or signalling molecules, growth factors and their receptors, and putative transcriptional factors, and their precise role remains to be investigated.
The evolution of vertebrate gastrulation.
- BiologyDevelopment (Cambridge, England). Supplement
This work attempts to identify homologous structures and equivalent stages in Xenopus, zebrafish, chick and mouse gastrulation by analyzing a head-organizer marker, goosecoid, and a marker common to all forming mesoderm, Brachyury.
Gastrulation in the mouse: The role of the homeobox gene goosecoid
Goosecoid is not an essential component of the mouse gastrula organizer but is required for craniofacial and rib development.
It is demonstrated that gsc is not essential for organizer activity in the mouse but is required later during embryogenesis for craniofacial and rib cage development and transplantation experiments suggest that the ovary does not provide gsc function to rescue gastrulation defects.
Gastrulation in Xenopus laevis: involution—a current view
The aim is to present the current view of how involution takes place in the dorsal involuting marginal zone of the Xenopus embryos.
Organizer-specific homeobox genes in Xenopus laevis embryos.
The dorsal blastopore lip of the early Xenopus laevis gastrula can organize a complete secondary body axis when transplanted to another embryo and the identification of four types of complementary DNAs from homeobox-containing genes that fulfill this criterion.
A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse.
Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo
- Biology, MedicineCurrent Biology
Drosophila goosecoid participates in neural development but not in body axis formation.
- BiologyThe EMBO journal
The results indicate that this invertebrate homolog of gsc is not required for gastrulation but plays a role in neurogenesis in post‐gastrula Drosophila embryos.