Mouse cerebellar adenosine-glutamate interactions and modulation of ethanol-induced motor incoordination.

  • Moahad Saeed Dar
  • Published 2002 in Alcoholism, clinical and experimental research


BACKGROUND It was demonstrated previously that cerebellar adenosine modulates ethanol-induced motor incoordination via A(1) subtype of adenosine receptors. Several reports suggest the involvement of brain glutamate mechanisms, in particular N-methyl-d-aspartate (NMDA) receptor sites, in the central nervous system (CNS) actions of ethanol. Mutually… (More)


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