Mouse breeds and the toxicity test for pertussis vaccine.

  • Merle Pittman
  • Published 1980 in Developments in biological standardization


Mice from 14 suppliers (breeders) responded significantly different in the mouse-weight-gain test for toxicity of pertussis vaccine. Seven-day weight gain varied by 2.4 fold (2.5 to 6.1 g) and did not correlate with normal gain. Weight gain expressed as percentage-weight gain of the control varied by two-fold (52 to 104%). The percentage-weight gain… (More)


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