Mouse blastomeres acquire ability to divide asymmetrically before compaction


The mouse preimplantation embryo generates the precursors of trophectoderm (TE) and inner cell mass (ICM) during the 8- to 16-cell stage transition, when the apico-basal polarized blastomeres undergo divisions that give rise to cells with different fate. Asymmetric segregation of polar domain at 8-16 cell division generate two cell types, polar cells which… (More)
DOI: 10.1371/journal.pone.0175032


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