Mouse T lymphoma cells contain a transmembrane glycoprotein (GP85) that binds ankyrin

  title={Mouse T lymphoma cells contain a transmembrane glycoprotein (GP85) that binds ankyrin},
  author={E L Kalomiris and Lilly Y. W. Bourguignon},
  journal={The Journal of Cell Biology},
  pages={319 - 327}
In this study we have used complementary biochemical and immunological techniques to establish that the lymphoma GP85 membrane glycoprotein is a transmembrane protein with a cytoplasmic domain that binds directly to ankyrin, a molecule known to link the membrane to the cytoskeleton. The evidence supporting our conclusion that the GP85 is a transmembrane glycoprotein is as follows: (a) GP85 can be surface-labeled with Na 125I and contains wheat germ agglutinin-binding sites, indicating that it… CONTINUE READING


Publications citing this paper.


Publications referenced by this paper.
Showing 1-10 of 36 references

Cloning of the P - subunit of the leukocyte adhesion proteins : homology to an extracellular matrix receptor defines a novel supergene family

  • U. K. Laemmli
  • 1987

LFA - I and Lyt - 2 , 3 , molecules associated with T - lymphocyte - mediated killing and Mac - l , an LFA - I homologue associated with complement receptor function , lmmunol

  • M. Staufenbiel
  • 1986

Similar Papers

Loading similar papers…