Mouse Plasmacytoid Cells : Long-lived Cells , Heterogeneous in Surface Phenotype and Function , that Differentiate Into CD 8 Dendritic Cells Only after Microbial Stimulus

@inproceedings{Okeeffe2002MousePC,
  title={Mouse Plasmacytoid Cells : Long-lived Cells , Heterogeneous in Surface Phenotype and Function , that Differentiate Into CD 8 Dendritic Cells Only after Microbial Stimulus},
  author={Meredith O’keeffe and Hubertus Hochrein and David Vremec and Irina Caminschi and Joanna Louise Miller and E. Margot Anders and Li Wu and Mireille H. Lahoud and Sandrine Henri and Bernadette J Scott and Paul J. Hertzog and Lilliana Tatarczuch and Ken Shortman},
  year={2002}
}
The CD45RA hi CD11c int plasmacytoid predendritic cells (p-preDCs) of mouse lymphoid organs, when stimulated in culture with CpG or influenza virus, produce large amounts of type I interferons and transform without division into CD8 CD205 DCs. P-preDCs express CIRE, the murine equivalent of DC-specific intercellular adhesion molecule 3 grabbing nonintegrin (DC-SIGN). P-preDCs are divisible by CD4 expression into two subgroups differing in turnover rate and in response to Staphylococcus aureus… CONTINUE READING
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