Mouse Piwi-interacting RNAs are 2′-O-methylated at their 3′ termini

@article{Kirino2007MousePR,
  title={Mouse Piwi-interacting RNAs are 2′-O-methylated at their 3′ termini},
  author={Yohei Kirino and Zissimos Mourelatos},
  journal={Nature Structural &Molecular Biology},
  year={2007},
  volume={14},
  pages={347-348}
}
Piwi-interacting RNAs (piRNAs) are a novel class of small RNAs that are expressed specifically and abundantly in male germ cells. Here we report that the 3′ termini of piRNAs are 2′-O-methylated; this modification may have important implications for the biogenesis and function of piRNAs. 

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