Mouse NKR-P1. A family of genes selectively coexpressed in adherent lymphokine-activated killer cells.

@article{Giorda1991MouseNA,
  title={Mouse NKR-P1. A family of genes selectively coexpressed in adherent lymphokine-activated killer cells.},
  author={Roberto Giorda and Massimo Trucco},
  journal={Journal of immunology},
  year={1991},
  volume={147 5},
  pages={1701-8}
}
NK cells are a subpopulation of large granular lymphocytes. They are able to recognize and lyse a wide variety of virally infected or neoplastic target cells without previous sensitization or MHC restriction. The molecules involved in target recognition and subsequent triggering of the killing process are still undefined. Recently, a 30-kDa protein highly expressed on rat NK cells and capable of mediating transmembrane signaling was identified and the gene coding for it cloned and sequenced. To… CONTINUE READING

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