Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis

@article{Wu1998MouseMF,
  title={Mouse Mesenchyme forkhead 2 (Mf2): expression, DNA binding and induction by sonic hedgehog during somitogenesis},
  author={Sareina C.-Y Wu and Justin C. Grindley and Glenn E. Winnier and Linda K. Hargett and Brigid L. M. Hogan},
  journal={Mechanisms of Development},
  year={1998},
  volume={70},
  pages={3-13}
}
Cloning and sequencing of mouse Mf2 (mesoderm/mesenchyme forkhead 2) cDNAs revealed an open reading frame encoding a putative protein of 492 amino acids which, after in vitro translation, binds to a DNA consensus sequence. Mf2 is expressed at high levels in the ventral region of newly formed somites, in sclerotomal derivatives, in lateral plate and cephalic mesoderm and in the first and second branchial arches. Other regions of mesodermal expression include the developing tongue, meninges, nose… CONTINUE READING