Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase

@inproceedings{Wojtasz2009MouseHA,
  title={Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase},
  author={Lukasz Wojtasz and Katrin Daniel and Ignasi Roig and Ewelina Bolcun-Filas and Huiling Xu and Verawan Boonsanay and Christian R Eckmann and Howard J. Cooke and Maria Jasin and Scott Keeney and Michael J. Mckay and Attila T{\'o}th},
  booktitle={PLoS genetics},
  year={2009}
}
Meiotic crossovers are produced when programmed double-strand breaks (DSBs) are repaired by recombination from homologous chromosomes (homologues). In a wide variety of organisms, meiotic HORMA-domain proteins are required to direct DSB repair towards homologues. This inter-homologue bias is required for efficient homology search, homologue alignment, and crossover formation. HORMA-domain proteins are also implicated in other processes related to crossover formation, including DSB formation… CONTINUE READING
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