Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers.

@article{Petersen2003MouseAH,
  title={Mouse A6-positive hepatic oval cells also express several hematopoietic stem cell markers.},
  author={Bryon E. Petersen and Brian Grossbard and Heather L Hatch and Liya Pi and Jie Deng and Edward W. Scott},
  journal={Hepatology},
  year={2003},
  volume={37 3},
  pages={632-40}
}
Hepatic oval cells (HOC) are thought to be a type of facultative stem cell that arises as a result of certain forms of hepatic injury. A new and more efficient model has been established to activate the oval cell compartment in mice by incorporating 3,5-diethoxycarbonyl-1,4-dihydro-collidine (DDC) in a standard chow at a concentration of 0.1%. At the present time, very few markers exist for the mouse oval cells. One accepted marker is A6, an uncharacterized epitope recognized by mouse hepatic… CONTINUE READING
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