Motor slowing and parkinsonian signs in aging rhesus monkeys mirror human aging.

@article{Zhang2000MotorSA,
  title={Motor slowing and parkinsonian signs in aging rhesus monkeys mirror human aging.},
  author={Zhi-Ming Zhang and Anders H. Andersen and Colin K. Smith and Richard C Grondin and Greg A. Gerhardt and Don Marshall Gash},
  journal={The journals of gerontology. Series A, Biological sciences and medical sciences},
  year={2000},
  volume={55 10},
  pages={B473-80}
}
Motor slowing is a universal feature of human aging, and parkinsonian signs are commonly expressed in human senescence. In the present study, age-associated declines in motor functions in 31 female rhesus monkeys were quantified by activity monitors and an automated test panel, and the incidence of parkinsonian signs was scored using a movement dysfunction assessment scale. Activity levels in middle-aged monkeys (12-17 years old) were less than half that of young animals (5-8 years old) and… CONTINUE READING