Motor skill learning depends on protein synthesis in motor cortex after training.

@article{Luft2004MotorSL,
  title={Motor skill learning depends on protein synthesis in motor cortex after training.},
  author={Andreas R{\"u}diger Luft and Manuel M. Buitrago and T. Ringer and Johannes Dichgans and J{\"o}rg Bernhard Schulz},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2004},
  volume={24 29},
  pages={6515-20}
}
The role of protein synthesis in memory consolidation is well established for hippocampus-dependent learning and synaptic plasticity. Whether protein synthesis is required for motor skill learning is unknown. We hypothesized that skill learning is interrupted by protein synthesis inhibition (PSI). We intended to test whether local protein synthesis in motor cortex or cerebellum is required during skill acquisition and consolidation. Anisomycin (ANI; 100 microg/microl in 1 microl of PBS… CONTINUE READING