Motor response to levodopa and the evolution of motor fluctuations in the first decade of treatment of Parkinson's disease.


Thirty-four patients with Parkinson's disease were followed for a mean period of 8 years from the time of initiation of levodopa medication. Levodopa response was charted from the starting point of pharmacological treatment to give a longitudinal point of view of the changes that evolve as the disease progresses. Objective measurements of the motor response… (More)


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