Motor reserve and novel area recruitment: amplitude and spatial characteristics of compensation in Parkinson's disease.

@article{Palmer2009MotorRA,
  title={Motor reserve and novel area recruitment: amplitude and spatial characteristics of compensation in Parkinson's disease.},
  author={Samantha J. Palmer and Bernard Ng and Rafeef Abugharbieh and Lisette Eigenraam and Martin J. McKeown},
  journal={The European journal of neuroscience},
  year={2009},
  volume={29 11},
  pages={2187-96}
}
Motor symptoms of Parkinson's disease (PD) do not appear until the majority of dopaminergic cells in the substantia nigra pars compacta are lost, suggesting significant redundancy or compensation in the motor systems affected by PD. Using functional magnetic resonance imaging, we examined whether compensation in PD is manifested by changes in amplitude and/or spatial extent of activity within normal networks (active motor reserve) and/or newly recruited regions [novel area recruitment (NAR… CONTINUE READING
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