Motor performance, exercise tolerance, and health-related quality of life in children on dialysis


In contrast to the adult population, little is known regarding health-related quality of life and exercise tolerance in children with end-stage renal disease (ESRD) undergoing chronic intermittent hemodialysis. We designed a pilot study to investigate whether research into this area is indicated. The aim of this study was to describe the motor skills, exercise tolerance, and health-related quality of life in children with ESRD. The study population consisted of ten hemodialysis patients (aged 7–16 years). In eight children motor proficiency according to Bruininks-Oseretsky was determined. In all ten children a progressive exercise test on a treadmill was performed. The results were compared with an age-matched healthy reference group. Nine children filled in the TNO-AZL Child Quality of Life (TACQOL) scoring list. One child had a markedly reduced fine motor skills capacity; another five children scored ≤−2 SD compared with healthy children in gross motor skills. Seven children showed a diminished VO2max (per kilogram body weight); six of these are physically inactive. Four of these seven children did not sustain the maximum workload. The self-assessed physical and mental health of children on dialysis seems comparable to the general population. We found no correlation between exercise performance or motor skills and hemoglobin levels, Kt/V, and time on dialysis. In conclusion, in this study most children had a reduced exercise tolerance and gross motor skills. There was no difference in fine motor skills. Pediatric dialysis patients report a good health-related quality of life.

DOI: 10.1007/s00467-004-1583-0

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@article{Eijsermans2004MotorPE, title={Motor performance, exercise tolerance, and health-related quality of life in children on dialysis}, author={Rian M. Eijsermans and Desir{\'e}e G W J Creemers and Paul J.M. Helders and Cock H. Schr{\"{o}der}, journal={Pediatric Nephrology}, year={2004}, volume={19}, pages={1262-1266} }