Motor outcome and allodynia are largely unaffected by novel olfactory ensheathing cell grafts to repair low-thoracic lesion gaps in the adult rat spinal cord.

@article{Deumens2013MotorOA,
  title={Motor outcome and allodynia are largely unaffected by novel olfactory ensheathing cell grafts to repair low-thoracic lesion gaps in the adult rat spinal cord.},
  author={Ronald Deumens and Sebastiaan van Gorp and Ahmet Bozkurt and Christina Beckmann and Tobias Fuehrmann and Kelsey Montzka and Rasha Tolba and Eiji Kobayashi and Ingo Heschel and Joachim Weis and Gary Brook},
  journal={Behavioural brain research},
  year={2013},
  volume={237},
  pages={185-9}
}
Olfactory ensheathing cells (OEC) are a promising graftable cell population for improving functional outcomes after experimental spinal cord injury. However only few studies have focused on experimental models with large cavitations, which require bridging substrates to transfer and maintain the donor cells within the lesion site. Here, a state-of-the-art collagen-based multi-channeled three dimensional scaffold was used to deliver olfactory ensheathing cells to 2 mm long unilateral low… CONTINUE READING
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