Motor map expansion following repeated cortical and limbic seizures is related to synaptic potentiation.

@article{Teskey2002MotorME,
  title={Motor map expansion following repeated cortical and limbic seizures is related to synaptic potentiation.},
  author={G. Campbell Teskey and M. -H Monfils and P. M. Vandenberg and Jeffrey Allan Kleim},
  journal={Cerebral cortex},
  year={2002},
  volume={12 1},
  pages={
          98-105
        }
}
The effect of experimentally induced seizure activity on the functional reorganization of motor maps has not previously been investigated. Furthermore, while the functional reorganization of motor maps has been thought to involve increases in synaptic communication, there has yet to be a test of this hypothesis. Here we show that repeated seizure activity (kindling), that is accompanied by increased synaptic strength within adult rat motor cortex, results in a doubling of the caudal forelimb… CONTINUE READING

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