Motor impairment in rats exposed to PCBs and methylmercury during early development.

@article{Roegge2004MotorII,
  title={Motor impairment in rats exposed to PCBs and methylmercury during early development.},
  author={Cindy S. Roegge and Victor Bo Chuan. Wang and Brian E. Powers and Anna Y. Klintsova and Samuel Simon Villareal and William T. Greenough and Susan L. Schantz},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2004},
  volume={77 2},
  pages={
          315-24
        }
}
Epidemiological and laboratory studies indicate that polychlorinated biphenyls (PCBs) and methyl mercury (MeHg) may have additive or interactive adverse effects on nervous system function. Prior studies have shown that high doses of MeHg target the cerebellum and impair balance and coordination, but the effects of PCBs on cerebellar function were unknown. In addition, the combined effects of PCBs and MeHg on cerebellar function have not been studied previously. Therefore, we investigated the… CONTINUE READING

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