Motor effect of dopamine on human sigmoid colon evidence for specific receptors

  title={Motor effect of dopamine on human sigmoid colon evidence for specific receptors},
  author={Giorgio Assuero Lanfranchi and Leonardo Marzio and Claudio Cortini and Eduardo Moreno Osset},
  journal={The American Journal of Digestive Diseases},
The effect of dopamine on human sigmoid motility has been studied in 26 subjects. To record mechanical activity of the sigmoid colon, two small, air-filled balloons mounted on a probe introduced through a sigmoidoscope were used. The recordings were made at a distance of 25 and 15 cm from the anal edge. Dopamine was infused for 10 min after a 30-min control infusion of physiologic solution. Mean amplitude, mean duration, mean frequency, percentage of motor activity, and motility index of the… CONTINUE READING


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