Motor Cortex Stimulation Suppresses Cortical Responses to Noxious Hindpaw Stimulation After Spinal Cord Lesion in Rats

@article{Jiang2014MotorCS,
  title={Motor Cortex Stimulation Suppresses Cortical Responses to Noxious Hindpaw Stimulation After Spinal Cord Lesion in Rats},
  author={Li Jiang and Yadong Ji and Pamela J. Voulalas and Michael L. Keaser and Hongbing Xiang and Rao P. Gullapalli and Joel D Greenspan and Radi Masri},
  journal={Brain Stimulation},
  year={2014},
  volume={7},
  pages={182-189}
}
BACKGROUND Motor cortex stimulation (MCS) is a potentially effective treatment for chronic neuropathic pain. The neural mechanisms underlying the reduction of hyperalgesia and allodynia after MCS are not completely understood. OBJECTIVE To investigate the neural mechanisms responsible for analgesic effects after MCS. We test the hypothesis that MCS attenuates evoked blood oxygen-level dependent signals in cortical areas involved in nociceptive processing in an animal model of chronic… CONTINUE READING
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