Motoneuron survival and expression of neuropeptides and neurotrophic factor receptors following axotomy in adult and ageing rats

@article{Johnson1998MotoneuronSA,
  title={Motoneuron survival and expression of neuropeptides and neurotrophic factor receptors following axotomy in adult and ageing rats},
  author={Ian Paul Johnson and R. M. Duberley},
  journal={Neuroscience},
  year={1998},
  volume={84},
  pages={141-150}
}
Three months after facial nerve transection, total numbers of motoneurons in the facial nucleus of six month (adult) Fischer 344 and Wistar rats were reduced to 83% and 75% of contralateral values, respectively (P < 0.05). This procedure in 22-26 month (ageing) Fischer 344 rats and Wistar rats resulted in a reduction of motoneuron numbers to 77% and 60% of the respective contralateral values (P < 0.05). Compared to adults, contralateral facial nuclei of aging Fischer 344 rats contained 10… CONTINUE READING
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