Motivational modulation of bradykinesia in Parkinson’s disease off and on dopaminergic medication

  title={Motivational modulation of bradykinesia in Parkinson’s disease off and on dopaminergic medication},
  author={Maja Kojovi{\'c} and Pablo Mir and Iris Trender-Gerhard and S. A. Schneider and Isabel Parees and Mark J. J. Edwards and Kailash P Bhatia and Marjan Jahanshahi},
  booktitle={Journal of Neurology},
Motivational influence on bradykinesia in Parkinson’s disease may be observed in situations of emotional and physical stress, a phenomenon known as paradoxical kinesis. However, little is known about motivational modulation of movement speed beyond these extreme circumstances. In particular, it is not known if motivational factors affect movement speed by improving movement preparation/initiation or execution (or both) and how this effect relates to the patients’ medication state. In the… CONTINUE READING
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