Motion-induced sickness following bilateral ablation of area postrema in squirrel monkeys.

@article{Wilpizeski1986MotioninducedSF,
  title={Motion-induced sickness following bilateral ablation of area postrema in squirrel monkeys.},
  author={Chester R. Wilpizeski and Louis D. Lowry and W S Goldman},
  journal={The Laryngoscope},
  year={1986},
  volume={96 11},
  pages={1221-5}
}
Using squirrel monkeys as experimental subjects, we reexamined the disputed role of the area postrema (AP) in motion-induced vomiting. After anesthetization, the obex and rhomboid fossa were exposed surgically, and the AP was ablated by thermal coagulation using either a battery cautery or a CO2 microsurgical laser. Sham operations were performed on another sample of monkeys. Two or more weeks after surgery, all animals were given 10 daily 2-hour horizontal rotations at 30 rpm. Every monkey in… CONTINUE READING