Motility of urease-deficient derivatives of Helicobacter pylori.

  title={Motility of urease-deficient derivatives of Helicobacter pylori.},
  author={Shumin Tan and Douglas E. Berg},
  journal={Journal of bacteriology},
  volume={186 3},
Early studies of a ureB mutant derivative of Helicobacter pylori had suggested that urease is needed for motility and that urease action helps energize flagellar rotation. Here we report experiments showing that motility is unaffected by deletion of ureA and ureB (urease genes) or by inactivation of ureB alone, especially if H. pylori strains used as recipients for transformation with mutant alleles are preselected for motility. This result was obtained with the strain used in the early studies… CONTINUE READING

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