Motility induction in breast carcinoma by mammary epithelial laminin 332 (laminin 5).

@article{Carpenter2009MotilityII,
  title={Motility induction in breast carcinoma by mammary epithelial laminin 332 (laminin 5).},
  author={Philip M. Carpenter and Anh V Dao and Zahida S Arain and Michelle Ker Xing Chang and Hoa Phuong Nguyen and Shehla Arain and Jessica Wang-Rodriguez and Soon-Young Kwon and Sharon P. Wilczynski},
  journal={Molecular cancer research : MCR},
  year={2009},
  volume={7 4},
  pages={462-75}
}
Host interactions with tumor cells contribute to tumor progression by several means. This study was done to determine whether mammary epithelium could interact with breast carcinoma by producing substances capable of inducing motility in the cancer cells. Conditioned medium of immortalized 184A1 mammary epithelium collected in serum-free conditions induced dose-dependent motility in the MCF-7 breast carcinoma cell line by both a semiquantitative scattering assay and a Boyden chamber assay… CONTINUE READING