Motif Participation by Genes in E. coli Transcriptional Networks

@article{Mayo2012MotifPB,
  title={Motif Participation by Genes in E. coli Transcriptional Networks},
  author={Michael L. Mayo and Ahmed Abdelzaher and Edward J. Perkins and Preetam Ghosh},
  journal={Frontiers in Physiology},
  year={2012},
  volume={3}
}
  • Michael L. Mayo, Ahmed Abdelzaher, +1 author Preetam Ghosh
  • Published 2012
  • Biology, Medicine
  • Frontiers in Physiology
  • Motifs are patterns of recurring connections among the genes of genetic networks that occur more frequently than would be expected from randomized networks with the same degree sequence. Although the abundance of certain three-node motifs, such as the feed-forward loop, is positively correlated with a networks’ ability to tolerate moderate disruptions to gene expression, little is known regarding the connectivity of individual genes participating in multiple motifs. Using the transcriptional… CONTINUE READING

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