Most of the avian genome appears available for retroviral DNA integration.

  • Arno Engelman
  • Published 1994 in
    BioEssays : news and reviews in molecular…


Although retroviral integration requires specific viral DNA sequences, factors which govern the choice of a chromosomal target site within an infected cell are less clear. For example, certain chromosomal regions may be inaccessible to the viral integration machinery, while others may favor integration. A recent paper by Withers-Ward et al.(1) addresses… (More)


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