Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure.

@article{Masoudi2003MostHO,
  title={Most hospitalized older persons do not meet the enrollment criteria for clinical trials in heart failure.},
  author={Frederick A. Masoudi and Edward P. Havranek and Pam Wolfe and Cary P Gross and Saif S. Rathore and John F. Steiner and Diana L Ordin and Harlan M. Krumholz},
  journal={American heart journal},
  year={2003},
  volume={146 2},
  pages={250-7}
}
BACKGROUND Although it is widely accepted that clinical trials in heart failure may not apply to older populations, the magnitude of the discrepancy between trial populations and patients seen in community-based practice are not known. Our objective was to determine the proportion of older persons meeting enrollment criteria of randomized controlled trials of agents that prolong life in heart failure. METHODS We conducted a cross-sectional study of Medicare beneficiaries >64 years old with… CONTINUE READING
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