Most blood biomarkers related to vitamin status, one-carbon metabolism, and the kynurenine pathway show adequate preanalytical stability and within-person reproducibility to allow assessment of exposure or nutritional status in healthy women and cardiovascular patients.

@article{Midttun2014MostBB,
  title={Most blood biomarkers related to vitamin status, one-carbon metabolism, and the kynurenine pathway show adequate preanalytical stability and within-person reproducibility to allow assessment of exposure or nutritional status in healthy women and cardiovascular patients.},
  author={Oivind Midttun and Mary Kay Townsend and Ottar K Nyg{\aa}rd and Shelley S Tworoger and Paul Brennan and Mattias Johansson and Per Magne Ueland},
  journal={The Journal of nutrition},
  year={2014},
  volume={144 5},
  pages={784-90}
}
Knowledge of stability during sample transportation and changes in biomarker concentrations within person over time are paramount for proper design and interpretation of epidemiologic studies based on a single measurement of biomarker status. Therefore, we investigated stability and intraindividual vs. interindividual variation in blood concentrations of biomarkers related to vitamin status, one-carbon metabolism, and the kynurenine pathway. Whole blood (EDTA and heparin, n = 12) was stored… CONTINUE READING
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