Most antidepressant drugs are safe for patients with epilepsy at therapeutic doses: A review of the evidence

@article{Kanner2016MostAD,
  title={Most antidepressant drugs are safe for patients with epilepsy at therapeutic doses: A review of the evidence},
  author={Andres Miguel Kanner},
  journal={Epilepsy & Behavior},
  year={2016},
  volume={61},
  pages={282-286}
}
For a long time, there has been a misconception that all antidepressant drugs have proconvulsant effects. Yet, antidepressants of the selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) families have been not only shown to be safe when used in patients with epilepsy (PWE) but have been found to display antiepileptic properties in animal models of epilepsy. In humans randomized to SSRIs vs. a placebo for the treatment of primary major depressive… CONTINUE READING
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