Mossy fiber sprouting in the fascia dentata after unilateral entorhinal lesions: Quantitative analysis using computer-assisted image processing

@article{West1984MossyFS,
  title={Mossy fiber sprouting in the fascia dentata after unilateral entorhinal lesions: Quantitative analysis using computer-assisted image processing},
  author={James R. West and Stephen L. Dewey},
  journal={Neuroscience},
  year={1984},
  volume={13},
  pages={377-384}
}
Axon sprouting typically occurs in a brain region that has been partially denervated. The present study demonstrates, quantitatively, evidence for sprouting outside the region of deafferentation. A modification of the Timm sulfide silver histochemical method was used to monitor an increase in the mossy fiber terminal field in the fascia dentata of adult rats following severe deafferentation of the outer three-fourths of stratum moleculare by unilateral entorhinal lesions. Computer-assisted… CONTINUE READING

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Nonobligate role of early or sustained expression of immediate-early gene proteins c-fos, c-jun, and Zif/268 in hippocampal mossy fiber sprouting.

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