Mosquito allergy: recombinant mosquito salivary antigens for new diagnostic tests.

@article{Simons2001MosquitoAR,
  title={Mosquito allergy: recombinant mosquito salivary antigens for new diagnostic tests.},
  author={F. Estelle R. Simons and Zhikang Peng},
  journal={International archives of allergy and immunology},
  year={2001},
  volume={124 1-3},
  pages={403-5}
}
In patients with mosquito allergy, lack of a readily available, sensitive, specific, safe test is the major obstacle to accurate diagnosis. Three recombinant mosquito salivary antigens, rAed a 1 (68 kD), rAed a 2 (37 kD) and rAed a 3 (30 kD), from Aedes aegypti have been cloned, expressed, purified and characterized. All three recombinant antigens are shared by Aedes vexans and other mosquito species, and all have been found to have biologic activity in humans. In recent studies, 43% of 28… CONTINUE READING

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