Mosaic-like organization of IgA protease genes in Neisseria gonorrhoeae generated by horizontal genetic exchange in vivo.

@article{Halter1989MosaiclikeOO,
  title={Mosaic-like organization of IgA protease genes in Neisseria gonorrhoeae generated by horizontal genetic exchange in vivo.},
  author={Roman Halter and Johannes Pohlner and Thomas F. Meyer},
  journal={The EMBO journal},
  year={1989},
  volume={8 9},
  pages={
          2737-44
        }
}
IgA protease is a putative virulence factor that exists in several allelic forms in Neisseria gonorrhoeae. However, extracellular secretion of these variant IgA proteases occurs by the same pathway involving three steps of autoproteolytic maturation from a large precursor. Two principal precursor types (H1 and H2) can be distinguished with respect to the location of autoproteolytic sites and the sizes of the mature products. By partial DNA sequence analysis, additional variations have been… CONTINUE READING
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