Mosaic distribution of opiate receptors, parafascicular projections and acetylcholinesterase in rat striatum

@article{Herkenham1981MosaicDO,
  title={Mosaic distribution of opiate receptors, parafascicular projections and acetylcholinesterase in rat striatum},
  author={Miles Herkenham and Candace B. Pert},
  journal={Nature},
  year={1981},
  volume={291},
  pages={415-418}
}
Although cell-stained sections have suggested heterogeneity in the neostriatum1, more conclusive evidence has come from selective neurochemical staining for receptors, enzymes or neural connections. For example, opiate receptors in the rat striatum are concentrated in discrete islands and in a streak under the corpus callosum2,3—regions that lack any visible morphological distinction. In the monkey, cortical afferent fibres terminate in intricate patterns4. In the cat striatum, variations in… CONTINUE READING

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