Morus alba L. Diminishes visceral adiposity, insulin resistance, behavioral alterations via regulation of gene expression of leptin, resistin and adiponectin in rats fed a high-cholesterol diet

 Morus alba L. Diminishes visceral adiposity, insulin resistance, behavioral alterations via regulation of gene expression of leptin, resistin and adiponectin in rats fed a high-cholesterol diet},
  author={Fateheya Mohamed Metwally and Hend Rashad and Asmaa Ahmed Mahmoud},
  journal={Physiology \& Behavior},

Effects of Tribulus terrestris, Avena sativa and White Ginseng on Adiponectin, Leptin, Resistin, Fatty Acid Binding Protein 4, Homocysteine and Paraoxonase-1 Levels in Hypercholesterolemic Rats

It was found that TT, AS and WG had positive effects on reversing the effects of hypercholesterolemia in rats and the combination treatment may have therapeutic effects in the treatment ofhypercholesterolesmia.

Ginkgo biloba extract (GbE) attenuates obesity and anxious/depressive-like behaviours induced by ovariectomy

GbE therapy was effective in attenuating the deleterious effects of ovariectomy on body composition, lipid profile, and anxious/depressive-like behaviours and further studies are warranted to better understand the therapeutic potential of GbE in menopause.

The effectiveness comparisons of eugenosedin-A, glibenclamide and pioglitazone on diabetes mellitus induced by STZ/NA and high-fat diet in SHR.

Eu-A could be used in the development of an effective agent for controlling DM and its complications by improving glucose, lipid homeostasis and anti-adrenergic, serotonergic activities.

Overnutrition Induced Cognitive Impairment: Insulin Resistance, Gut-Brain Axis, and Neuroinflammation

It is concluded that before the onset of obesity, short-term exposure to high-nutrition diets already blunted central responses to insulin, altered gut microbiome composition, and activated inflammatory mediators.

Anti-obesity and Hypolipidemic Effects of Morus alba- A Review

The prevalence of obesity was worldwide increase in the last 60 years and it markedly increased the incidence of many diseases: fatty liver, type 2 diabetes, hypertension, ischemic heart diseases, sleep apnea, osteoporosis, dementia, tumors and many other disorders.

The functional nutritional and regulatory activities of calcium supplementation from eggshell for obesity disorders management.

It was concluded that there was good evidence that diets supplemented with ES were associated with the reduction of obesity complications especially regulating fat processing and storage in the body.

Effect of Houttuynia cordata Thunb. Extract in High-Fat Diet-Induced Obese Rats

It’s time to dust off the gloves and get ready for the cold weather.



Quercetin Ameliorates Metabolic Syndrome and Improves the Inflammatory Status in Obese Zucker Rats

Both doses of quercetin improved dyslipidemia, hypertension, and hyperinsulinemia in obese Zucker rats, but only the high dose produced antiinflammatory effects in VAT together with a reduction in body weight gain.

Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice.

Chronic dietary intake of quercetin reduces liver fat accumulation and improves systemic parameters related to metabolic syndrome, probably mainly through decreasing oxidative stress and reducing PPARα expression, and the subsequent reduced expression in the liver of genes related to steatosis.

Direct comparison of metabolic health effects of the flavonoids quercetin, hesperetin, epicatechin, apigenin and anthocyanins in high-fat-diet-fed mice

All flavonoids lowered parameters of HF-induced adiposity, with quercetin being most effective.

Consumption of polyphenol-rich Morus alba leaves extract attenuates early diabetic retinopathy: the underlying mechanism

The results indicate that M. alba has protective effect on diabetic retinopathy with possible mechanisms of inhibiting hyperglycemia-induced oxidative stress, apoptosis, inflammation, polyol pathway activation, and VEGF expression in the retina.

Quercetin suppresses immune cell accumulation and improves mitochondrial gene expression in adipose tissue of diet‐induced obese mice

Comprehensive gene expression analysis revealed that quercetin suppressed gene expression associated with the accumulation and activation of immune cells, including macrophages and lymphocytes in EAT, and markedly increased gene expressionassociated with mitochondrial oxidative phosphorylation and mitochondrial DNA content.

Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice.

  • Ae-Sim ChoS. Jeon Mi-Kyung Lee
  • Biology
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2010