Mortality in patients with septic shock correlates with anti-inflammatory but not proinflammatory immunomodulatory molecules.

@article{Pablo2011MortalityIP,
  title={Mortality in patients with septic shock correlates with anti-inflammatory but not proinflammatory immunomodulatory molecules.},
  author={Ra{\'u}l de Pablo and Jorge Monserrat and Eduardo Dopico Reyes and David D{\'i}az-Mart{\'i}n and Manuel Rodriguez Zapata and Fernando Carballo and Antonio de la Hera and A. R. Prieto and Melchor {\'A}lvarez-Mon},
  journal={Journal of intensive care medicine},
  year={2011},
  volume={26 2},
  pages={125-32}
}
BACKGROUND Mortality in patients with septic shock remains unacceptably high and the attempts to antagonize certain proinflammatory cytokines based on the results of animal model studies have failed to improve survival rates. The objective of this article is to examine the pro-/anti-inflammatory cytokine balance in patients with septic shock and its connection with mortality. METHODS Serum levels of proinflammatory cytokines (tumor necrosis factor-α [TNF-α], interleukin 1β [IL-1β], interferon… CONTINUE READING