Mortality in epilepsy

@article{Hitiris2007MortalityIE,
  title={Mortality in epilepsy},
  author={Nikolas Hitiris and Rajiv Mohanraj and John Norrie and Martin J Brodie},
  journal={Epilepsy \& Behavior},
  year={2007},
  volume={10},
  pages={363-376}
}

Mortality due to SUDEP and status epilepticus.

TLDR
Estimates indicate that mortality in patients with epilepsy due to SUDEP and SE account for between 48 and 162 deaths per year in Ireland and sources of mortality information currently available possibly underestimate the numbers involved especially if deaths due to non-convulsive status are included.

Reducing Sudden Unexpected Death in Epilepsy: Considering Risk Factors, Pathophysiology and Strategies

TLDR
Risk factors and possible pathophysiological mechanisms are described and discussed to elucidate possible preventative strategies to avertudden Unexpected Death in Epilepsy and methods to prevent SUDEP are proposed.

AWARENESS OF SUDDEN UNEXPECTED DEATH IN EPILEPSY AMONG NEUROLOGISTS IN LATVIA

TLDR
Evidence from epidemiologic, observational, clinical, and pathological studies strongly suggests that in most cases, sudden unexpected death in epilepsy occurs after a seizure, usually a tonic– clonic seizure.

Mortality from sudden unexpected death in epilepsy (SUDEP) in a cohort of adults with intellectual disability.

TLDR
It is found that in the majority of ID cases there was little detailed documentation on the circumstances surrounding deaths, no communication with patients/carers about risk of SUDEP and an absence of post-mortem reports or carers' referral for bereavement counselling.

The burden of premature mortality of epilepsy in high‐income countries: A systematic review from the Mortality Task Force of the International League Against Epilepsy

TLDR
Prior reviews of mortality in epilepsy are updated to reevaluate and quantify the risks, potential risk factors, and causes of these deaths and to identify those studies likely to accurately quantify these risks in representative populations.

Lesiones, accidentes y mortalidad en epilepsia: Una revisión de sus prevalencias, factores de riesgo y prevención

TLDR
Information about specific type of injuries in patients with epilepsy, such as fractures, burns, concussions, dislocations, etc, is reviewed in a comprehensive way.

A review of sudden unexpected death in epilepsy: Prediction of patients at risk

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References

SHOWING 1-10 OF 147 REFERENCES

Sudden Death in Epilepsy: A Study of Incidence in a Young Cohort with Epilepsy and Learning Difficulty

TLDR
All 14 sudden deaths occurred when the pupils were not under the close supervision of the school and most were unwitnessed, which has implications for prevention.

Mortality in Patients with Epilepsy

TLDR
Standardized mortality ratios (SMR) were determined for a cohort of patients with first diagnosis of epilepsy as residents of Rochester, Minnesota, between 1935 and 1974, suggesting that factors other than seizure occurrence affect mortality.

Incidence and risk factors in sudden unexpected death in epilepsy

TLDR
The results support the idea that tonic-clonic seizures are an important proximate cause of SUDEP, and create a risk profile for SUDEP that may help direct preventative efforts.

Mortality in epilepsy

TLDR
Fatal driver crashes due to seizures are uncommon, and this finding supports the current public policy of permitting patients whose seizures are controlled to drive.

Do Antiepileptic Drugs Play a Role in Sudden Unexpected Death in Epilepsy?

TLDR
Best current evidence indicates that the risk of SUDEP can be decreased by aggressive treatment of tonic-clonic seizures with as few antiepileptic drugs as necessary to achieve complete control.

Remote symptomatic epilepsy

TLDR
Persistent seizures are associated with increased mortality in remote symptomatic epilepsy, and Mortality is highest among individuals with status epilepticus or generalized convulsions.

Premature mortality in people with epilepsy in rural China: a prospective study

Epilepsy and Mortality Rate and Cause of Death

TLDR
The death of 218 persons known to have epilepsy in Warsaw was most often due to epilepsy, i.e., death in a convulsion or due to accident related to seizures, followed by brain tumor and heart disease, and in 97 institutionalized patients death in status or with pneumonia or heart disease was most frequent.
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