Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis

@article{Chu2018MortalityAM,
  title={Mortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis},
  author={D. Chu and L. Kim and P. Young and N. Zamiri and Saleh A. Almenawer and Roman Jaeschke and W. Szczeklik and H. Sch{\"u}nemann and J. Neary and W. Alhazzani},
  journal={The Lancet},
  year={2018},
  volume={391},
  pages={1693-1705}
}
BACKGROUND Supplemental oxygen is often administered liberally to acutely ill adults, but the credibility of the evidence for this practice is unclear. [...] Key Method Studies limited to patients with chronic respiratory diseases or psychiatric disease, patients on extracorporeal life support, or patients treated with hyperbaric oxygen therapy or elective surgery were excluded. We screened studies and extracted summary estimates independently and in duplicate.Expand
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