Mortality and morbidity attributable to inadequate empirical antimicrobial therapy in patients admitted to the ICU with sepsis: a matched cohort study.

@article{GarnachoMontero2008MortalityAM,
  title={Mortality and morbidity attributable to inadequate empirical antimicrobial therapy in patients admitted to the ICU with sepsis: a matched cohort study.},
  author={Jos{\'e} Garnacho-Montero and Carlos Ort{\'i}z-Leyba and Inmaculada Herrera-Melero and Teresa Aldab{\'o}-Pall{\'a}s and Aurelio Cayuela-Dom{\'i}nguez and Juan Antonio M{\'a}rquez-V{\'a}caro and Jesus Carbajal-Guerrero and Jos{\'e} Luis Garc{\'i}a-Garmendia},
  journal={The Journal of antimicrobial chemotherapy},
  year={2008},
  volume={61 2},
  pages={436-41}
}
OBJECTIVES To determine the attributable mortality and excess length of stay (LOS) associated with the use of inadequate empirical antimicrobial therapy in patients with sepsis at admission to the intensive care unit (ICU). METHODS A retrospective matched cohort study was performed using a prospectively collected database at a 40 bed general ICU at a university public hospital. Patients who received inadequate antimicrobial therapy at admission to the ICU (exposed) were matched with controls… CONTINUE READING

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