Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data

  title={Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease: a pooled analysis of individual patient data},
  author={Stuart J. Head and Milan Milojevic and Joost Daemen and Jung‐Min Ahn and Eric Boersma and Evald H{\o}i Christiansen and Michael J. Domanski and Michael E Farkouh and Marcus D Flather and Valent{\'i}n Fuster and Mark A. Hlatky and Niels Ramsing Holm and Whady Hueb and Masoor Kamalesh and Young-Hak Kim and Timo M{\"a}kikallio and Friedrich W. Mohr and Grigorios Papageorgiou and Seung‐Jung Park and Alfredo E. Rodr{\'i}guez and Joseph F Sabik and Rodney Hilton Stables and Gregg W. Stone and Patrick Wjc Serruys and Arie Pieter Kappetein},
  journal={The Lancet},

Figures and Tables from this paper

Coronary artery disease: Mortality after CABG surgery versus PCI
These results help affirm CABG [surgery] as the treatment of choice when revascularization in patients with complex multivessel disease and diabetes is deemed to be necessary, according to a new meta-analysis in The Lancet.
Stent versus Coronary Artery Bypass Surgery in Multi-Vessel and Left Main Coronary Artery Disease: A Meta-Analysis of Randomized Trials with Subgroups Evaluation
Compared with CABG, PCI using Stents showed lower 30 days mortality, higher late mortality and lower incidence of stroke and diabetes and a high SYNTAX score were the subgroups that influenced more adversely the results of PCI.
Coronary artery bypass confers intermediate-term survival benefit over percutaneous coronary intervention with new-generation stents in real-world patients with multivessel coronary artery disease, including left main disease: a retrospective analysis of 6383 patients.
  • V. Panoulas, C. Ilsley, S. Raja
  • Medicine
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
  • 2019
In this contemporary cohort of real-world patients with MVD, CABG was associated with increased intermediate-term survival compared to PCI with new-generation drug-eluting stents.


Five-Year Outcomes in Patients With Left Main Disease Treated With Either Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting in the Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery Trial
This analysis compares 5-year clinical outcomes in PCI- and CABG-treated LM patients in the Synergy Between PCI With Taxus and Cardiac Surgery (SYNTAX) trial and suggests that both treatments are valid options for LM patients.
Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease.
CABG remains the standard of care for patients with three-vessel or left main coronary artery disease, since the use of CABG, as compared with PCI, resulted in lower rates of the combined end point of major adverse cardiac or cerebrovascular events at 1 year.
Coronary artery bypass grafting vs. percutaneous coronary intervention for patients with three-vessel disease: final five-year follow-up of the SYNTAX trial.
Five-year results of patients with 3VD treated with CABG or PCI using the first-generation paclitaxel-eluting DES suggest that CABGs should remain the standard of care as it resulted in significantly lower rates of death, MI, and repeat revascularization, while stroke rates were similar.
Long-Term Safety and Efficacy of Percutaneous Coronary Intervention With Stenting and Coronary Artery Bypass Surgery for Multivessel Coronary Artery Disease: A Meta-Analysis With 5-Year Patient-Level Data From the ARTS, ERACI-II, MASS-II, and SoS Trials
In this pooled analysis of 4 randomized trials, PCI with stenting was associated with a long-term safety profile similar to that of CABG, however, as a result of persistently lower repeat revascularization rates in the C ABG patients, overall major adverse cardiac and cerebrovascular event rates were significantly lower in theCABG group at 5 years.
Randomized trial of stents versus bypass surgery for left main coronary artery disease.
In this randomized trial involving patients with unprotected left main coronary artery stenosis, PCI with sirolimus-eluting stents was shown to be noninferior to CABG with respect to major adverse cardiac or cerebrovascular events, but the results cannot be considered clinically directive.