Mortality Risk of Hypnotics: Strengths and Limits of Evidence

@article{Kripke2015MortalityRO,
  title={Mortality Risk of Hypnotics: Strengths and Limits of Evidence},
  author={D. Kripke},
  journal={Drug Safety},
  year={2015},
  volume={39},
  pages={93-107}
}
  • D. Kripke
  • Published 2015
  • Medicine
  • Drug Safety
  • Sleeping pills, more formally defined as hypnotics, are sedatives used to induce and maintain sleep. In a review of publications for the past 30 years, descriptive epidemiologic studies were identified that examined the mortality risk of hypnotics and related sedative–anxiolytics. Of the 34 studies estimating risk ratios, odds ratios, or hazard ratios, excess mortality associated with hypnotics was significant (p < 0.05) in 24 studies including all 14 of the largest, contrasted with no studies… CONTINUE READING

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 94 REFERENCES
    Is usage of hypnotics associated with mortality?
    78
    Association between hypnotics use and increased mortality: causation or confounding?
    23
    Effect of anxiolytic and hypnotic drug prescriptions on mortality hazards: retrospective cohort study
    98
    Hypnotics' association with mortality or cancer: a matched cohort study
    305