Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.

Abstract

Preclinical studies using human gastric adenocarcinoma (GAC) cell lines have shown that the mammalian target of rapamycin (mTOR) inhibitor, rapamycin, can inhibit tumor growth and that the extracellular signal-regulated kinase (ERK) of the Ras/Raf kinase/ERK pathway is related to chemoresistance and apoptosis. We examined the state of activation of… (More)

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Cite this paper

@article{Feng2008MorphoproteomicPO, title={Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.}, author={Wei Feng and Robert E. Brown and Camtu D Trung and Wei Li and Liwei Wang and Thaer Khoury and Sadir J. Alrawi and James Yudong Yao and Keping Xia and Dongfeng Tan}, journal={Annals of clinical and laboratory science}, year={2008}, volume={38 3}, pages={195-209} }