Morphometry of the human cortex cerebri and corpus striatum during aging

@article{Haug1991MorphometryOT,
  title={Morphometry of the human cortex cerebri and corpus striatum during aging},
  author={Herbert Haug and Reinhard Eggers},
  journal={Neurobiology of Aging},
  year={1991},
  volume={12},
  pages={336-338}
}
The commentary is based on our results of biological aging research with the following findings: a loss of neurons cannot be found, the size of neurons and the number of synapses decrease with age, the various regions of brain react quite differently. Altogether, these results speak for "use it or lose it." However, the genetically determined decreased brain function during aging can only be inhibited, not permanently preserved. 
Neuromorphological Changes in Neuronal and Neuroglial Populations of the Cerebral Cortex in the Aging Rat
TLDR
The heterogeneity of the studies, as well as the fact that the effects of aging differ in cerebral zones, animal models, and individuals, are the main causes of these discrepancies. Expand
The effect of ageing on neurones in the visual sector of the thalamic reticular nucleus
TLDR
This paper studies the quantitative morphological changes occurring during ageing in neurones of the dorsocaudal or visual sector of the thalamic reticular nucleus of Wistar rats using morphometric methods. Expand
Impact of aging brain circuits on cognition
TLDR
There is remarkable consistency in the pattern of age‐related neural and cognitive change observed in healthy humans and other animals, including changes in cognitive operations that are known to be dependent on the hippocampus, as well as those requiring intact prefrontal cortical circuits. Expand
Histology and histochemistry of the aging cerebral cortex: An overview
TLDR
This review contributes to a new vision of the most important findings in the aging cerebral cortex as elucidated by modern histology and histochemistry as well as the implications of nitric oxide in this process. Expand
Correlation of cognitive performance and morphological changes in neocortical pyramidal neurons in aging
TLDR
The data suggest that both cholinergic atrophy and an imbalance towards inhibition may contribute to the observed age-associated behavioral impairment. Expand
Training-Induced Brain Structure Changes in the Elderly
TLDR
Elderly persons were able to learn three-ball cascade juggling, but with less proficiency compared with 20-year-old adolescents, and gray-matter changes in the older brain related to skill acquisition were observed in area hMT/V5 (middle temporal area of the visual cortex). Expand
Insights into the ageing mind: a view from cognitive neuroscience
TLDR
Much remains unknown about how normal ageing affects the neural basis of cognition, but recent research on individual differences in the trajectory of ageing effects is helping to distinguish normal from pathological origins of age-related cognitive changes. Expand
Normal Aging in the Cerebral Cortex of Primates
TLDR
Normal aging changes are important to understand both in their own right and because they constitute the baseline upon which the changes brought about by Alzheimer’s disease are superimposed. Expand
Aging, intelligence, and anatomical segregation in the frontal lobes
Abstract In this paper we propose a specific neuroanatomical theory of cognitive aging. We review evidence supporting the growing consensus that normal adult age changes reflect differentialExpand
Variation in hippocampal neuron number with age and brain volume.
TLDR
The findings of this study show that, in neurologically normal individuals, brain size is a major determinant of the number of CA1 neurons. Expand
...
1
2
3
4
5
...

References

SHOWING 1-2 OF 2 REFERENCES
Preliminary report on macroscopic age changes in the human prosencephalon. A stereologic investigation.
TLDR
The studies here reported were performed on the prosencephalons of 12 human brains between 37 and 86 years of age having no signs of neuropathological alteration, and the relative volumes and surface areas of the frontal lobe and the Prosencephalic ganglia decrease with aging, while the parieto-occipitals and the striate cortex increase. Expand
The significance of morphometric procedures in the investigation of age changes in cytoarchitectonic structures of human brain.
TLDR
The investigations were performed on NISSL-stained cytoarchitectonic images of totally 78 human brains in the frontal area 11 (inside sulcus olfactorius) and in the visual cortex (area 17) with 60 samples and the main result is that every gray structure of the brain has its own history. Expand