Morphometric changes of gray matter in Parkinson's disease with depression: a voxel-based morphometry study.

@article{Feldmann2008MorphometricCO,
  title={Morphometric changes of gray matter in Parkinson's disease with depression: a voxel-based morphometry study.},
  author={{\'A}d{\'a}m Feldmann and Zsolt Illes and P{\'e}ter Kosztol{\'a}nyi and Eniko Illes and Andrea Mike and Ferenc Kover and Istv{\'a}n Bal{\'a}s and Norbert Kov{\'a}cs and Ferenc Nagy},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  year={2008},
  volume={23 1},
  pages={
          42-6
        }
}
The origin of the high rate of depression in idiopathic Parkinson's disease (PD) is unknown. We applied voxel-based morphometry (VBM), as a sensitive tool in detection of gray matter MR density alterations, to find differences in depressed and nondepressed PD patients. Patients with idiopathic PD were classified into depressed (DPD) and nondepressed (NDPD) groups based on the Montgomery-Asberg Depression Rating Scale (MADRS). Subsequently, a group comparisons were performed between depressed PD… CONTINUE READING
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