Morphometric analysis of the forebrain anomalies in the delayed Splotch mutant embryo.

@article{OShea1987MorphometricAO,
  title={Morphometric analysis of the forebrain anomalies in the delayed Splotch mutant embryo.},
  author={Kathy Sue O'Shea and J. S. T. Rheinheimer and John M. O'Shea},
  journal={Journal of craniofacial genetics and developmental biology},
  year={1987},
  volume={7 4},
  pages={357-69}
}
The early development of delayed Splotch mouse embryos was examined histologically using scanning electron microscopy and morphometric techniques. Embryos obtained from matings of mice heterozygous for the delayed Splotch gene exhibited a high incidence of lumbosacral (25%) or cephalic (7%) neural tube defects. The lumbosacral neural tube defects extended… CONTINUE READING